Historisch-demografisch onderzoek van Wevelgem, 1754-1796
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چکیده
منابع مشابه
Dmd052514 1787..1796
Failure in amyloid-b (Ab) systemic clearance across the liver has been suggested to play a role in Ab brain accumulation and thus to contribute largely to the pathology of Alzheimer’s disease (AD). The purpose of this study was to characterize in vitro the transport mechanisms of Ab40 across the liver using sandwich-cultured primary rat hepatocytes (SCHs) and to determine its biliary clearance ...
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CYP3A5 plays a prominent role in the metabolism of maraviroc, an approved drug for human immunodeficiency virus (HIV)-1 treatment and a candidate for HIV-1 prevention. We studied the effect of the CYP3A5 genotype on pharmacokinetics of maraviroc and a primary CYP3A5-dependent metabolite of maraviroc denoted as metabolite 1 (M1). Volunteers were screened for health status and CYP3A5 genotype (wi...
متن کاملWiltshire Coroners' Bills 1752–1796
absence of any restraint upon the author's curiosity by the need to attend to a specific problem. This author is indeed inquisitive: he exploits analogies from all the natural world to explain physiological processes, and he is probably the first person known to have modified an existing object to make an apparatus for use in demonstration. Analogical reasoning and experiment loom large in thes...
متن کاملDdh180 1745..1754
Parkinson’s disease (PD) is characterized by the selective degeneration of dopaminergic (DA) neurons in substantia nigra pars compacta (SNpc). A combination of genetic and environmental factors contributes to such a specific loss. Among the five PD-linked genes identified so far, parkin, a protein-ubiquitin E3 ligase, appears to be the most prevalent genetic factor in PD. Although a variety of ...
متن کاملThe Pre-analytical Phase of Pathology Research and Diagnostics De Pre-analytische Fase van Pathologie Onderzoek en Diagnostiek
Variation in pre-analytical procedures can have effects on RNA expression in tissue. Standardization of the pre-analytical workflow is not always an option, therefore it is necessary to know which factors might be of influence and should be noted as meta data in tissuebank databases. Here we describe the discovery and potential use of a RT-qPCR fingerprint of genes sensitive to the ischemic per...
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ژورنال
عنوان ژورنال: Handelingen van het Genootschap voor Geschiedenis
سال: 2000
ISSN: 0770-0822
DOI: 10.21825/hvgg.v137i3-4.18970